Good times...
...but it could be much, much more. You're one of the most clever sprite choreographers I know but I feel that you've hit a plateau on the technical end. I've said this a dozen times and I'll say it once again - get Photoshop and learn how to use it.
You're probably sick of hearing that, so let's get to the stylistic stuff.
While the action was well-done and the story was pleasingly in-depth, I found it a bit tiring to have so much detail thrown at me all at once story-wise. The biographies were more confusing than helpful considering the amount of information displayed for characters that weren't really involved. It might prove more illuminating to get into that information later on when their involvement becomes more prominent. Generally speaking, stuff like that should provide a few (but not too many) answers and not create additional questions.
While I was glad to see Reiko take part in the action, his presence struck me as being pretty much random. The series tie-in potential is interesting, but I would have liked to have seen him make a bigger impact rather than be a wildcard for Bishop/Cyke/Sabes.
Also, directional tails for speech bubbles don't have to go all the way to the mouth. A simple short point will do the job and look less distracting.
Well, those are my thoughts. I hope you find at least some of it useful and constructive.
5/5 9/10
R1665